Services

National Glycoscience Resource NGlycoR@CCRC

Through the “National Glycoscience Resource”  (NIH grant R24GM137782), we provide services and training for the structural characterization of all types of glycoconjugates to the greater biomedical scientific community including universities, minority serving institutions, federal agencies, biotechnology, and pharmaceutical industries. Our plant characterization projects are supported by an additional grant from the Department of Energy “Center for Plant and Microbial Complex Carbohydrates” (DE-SC0015662).The particular combination of technologies applied for this purpose will depend on the specific structural information desired by the user and will be determined individually after discussion with Dr. Azadi.

Plant Carbohydrates

• Isolation/Purification
• Polysaccharide Structure
• Hemicellulose/Cellulose
• Fungal/Glucans
• Lignin Analysis
• Absolute Configuration

Glycomics/Glycoproteomics

• Glycomics
• Glycan Sequencing
• Glycoproteomics
• Sites Of Glycosylation
• Monosaccharide/Linkage
• Sialic Acids
• Glycolipids
• Milk Oligosaccharides

Biosimilars

• Antibody/ Glycoprotein Structure Analysis
• Heparin /LMW Heparins
• Iron Carbohydrate Complexes
• Peptide/Protein
• Higher Order Structure

Techniques

• 1D And 2D NMR
• ESI-MS/MALDI-MS
• GC-MS
• CE/CE-MS
• HPAEC
• HPLC

Microbial Carbohydrates

• Isolation /Purification
• CPS/LPS/EPS Structure
• Lipid A Structure
• Peptidoglycan
• Fatty Acids
• Absolute Configuration

Glycosaminoglycans

• Isolation/Purification
• Disaccharide Analysis
• Structural Analysis
• MS/NMR
• Biosimilars

Additional Services

• Hands-On Training
• GC-EIMS PMAAs Database
• Xyloglucan NMR Database
• Molecular Modeling
• QRT-PCR
• Surface Plasmon Resonance (SPR)
• Nucleotide Sugars and MAB
• Bio-Layer Interferometry (BLI)
• Standards

NMR Services

• 1 D NMR
• 2 D NMR
• Characterization of Insoluble Polysaccharides
• Sequential Determination of Polysaccharides
• Molecular Weight Determination (DOSY)
• Solid State NMR (CP-MAS & HR-MAS)
• Characterization of Biosimilars