The Analytical Service and Training Laboratory is a unique facility with state-of-the-art instrumentation designed for detailed structural elucidation of complex carbohydrates.


We have MALDI-TOF and MALDI-TOF/TOF and electrospray and nanospray ionization techniques coupled with ion trap and Orbitrap mass analyzers including a thermo fusion tribrid mass spectrometry instrument. We perform tandem mass spectrometry using CID, HCD and ETD fragmentation and ion activation mechanisms for compositional and sequence analysis of N and O linked glycans and glycopeptides.


One dimensional and two dimensional Nuclear Magnetic Resonance spectroscopy is used for the comprehensive structural analysis and repeating unit sequencing of polysaccharides and the full structural characterization of polysaccharides and glycans. Non carbohydrate substituents and molecular carbohydrate protein interactions can also be determined.


Mass Spectrometry

Thermo Orbitrap Fusion Tribrid with Nano-HPLC1
Thermo Velos-Orbitrap-Elite with UHPLC1
Thermo LTQ-Orbitrap with Nano-UHPLC1
Bruker Microflex LRF MALDI-TOF1
Shimadzu Ultra GC-MS with CI Source1
Agilent GC-MS with EI Source5
Quantum Pyrolysis, Extrel Molecular-Beam-MS1
Quantum Pyrolysis, Agilent GC-MS1
Beckman Coulter CE 8000SI Interfaced to Thermo LTQ-MS1
Gas Chromatography Mass Spectrometry


Shimadzu Ultra GC-FID1
Dionex HPAEC with PAD Detector2
Agilent HPLC with UV, Fluorescent, RI, ELSD and CAD Detectors5
Beckman Coulter CE PA800 with UV, PDA LIF (488 em, 570 ex)1
Chromatography instrumentation Complex Carbohydrate

NMR Spectrometers

Varian 900 FT-NMR1
Varian Inova 800 FT-NMR1
Varian Inova 600 FT-NMR1
Varian Inova 500 FT-NMR1
Varian Mercury 300 FT-NMR2
Nuclear Magnetic Resonance
NMR Analysis


Thermo Scientific Orbitor RS with Biotek Multiflo, EL406, EON and Precision XS1
Thermo Scientific instrumentation Complex Carbohydrate