News and Events

Primary Publications

Site Specific N- and O-glycosylation mapping of the Spike Proteins of SARS-CoV-2 Variants of Concern.
Shajahan A, Pepi L, Kumar B, Murray N, Azadi P. Site Specific N- and O-glycosylation mapping of the Spike Proteins of SARS-CoV-2 Variants of Concern.
Read Full Article: DOI: 10.21203/rs.3.rs-2188138/v1

Pregnancy enables antibody protection against intracellular infection (2022)
Erickson JJ, Archer-Hartmann S, Yarawsky AE, Miller JLC, Seveau S, Shao TY, Severance AL, Miller-Handley H, Wu Y, Pham G, Wasik BR, Parrish CR, Hu YC, Lau JTY, Azadi P, Herr AB, Way SS.
Read Full Article: doi: 10.1038/s41586-022-04816-9

Surface Anchoring of the Kingella kingae Galactan Is Dependent on the Lipopolysaccharide O-Antigen.
Montoya NR, Porsch EA, Muñoz VL, Muszyński A, Vlach J, Hahn DK, Azadi P, Sherman M, Yang H, Chandler CE, Ernst RK, St Geme JW 3rd. Surface Anchoring of the Kingella kingae Galactan
Read Full Article: doi: 10.1128/mbio.02295-22.

Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter.
Spellmon N, Muszyński A, Górniak I, Vlach J, Hahn D, Azadi P, Zimmer J.
Read Article: doi: 10.1038/s41467-022-32597-2.
Young ID, Nepogodiev SA, Black IM, Le Gall G, Wittmann A, Latousakis D, Visnapuu T, Azadi P, Field RA, Juge N, Kawasaki N.
Read Full Article:doi: 10.1016/j.carbpol.2021.118606.

Lipopolysaccharide associated with β-2,6 fructan mediates TLR4-dependent immunomodulatory activity in vitro. Carbohydr Polym.
Young ID, Nepogodiev SA, Black IM, Le Gall G, Wittmann A, Latousakis D, Visnapuu T, Azadi P, Field RA, Juge N, Kawasaki N.  doi: 10.1016/j.carbpol.

A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface.
Wu H, Shajahan A, Yang JY, Capota E, Wands AM, Arthur CM, Stowell SR, Moremen KW, Azadi P, Kohler JJ. A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface.
Read Full Article: doi: 10.1016/j.chembiol.2021.07.00.7

Desialylation of O-glycans activates von Willebrand factor by destabilizing its autoinhibitory module.
Voos KM, Cao W, Arce NA, Legan ER, Wang Y, Shajahan A, Azadi P, Lollar P, Zhang XF, Li R.
Read Full Article: doi: 10.1111/jth.15528.

Comprehensive characterization of N-and O-glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2(2020)
Shajahan A, Archer-Hartmann SA, Supekar NT, Gleinich AS, Heiss C, Azadi P
Read Full Article: http://doi.org/10.1101/2020.05.01.071688

Deducing the N-and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2(2020)
Shajahan A, Supekar NT, Gleinich AS, Azadi P
Read Full Article:http://doi.org/10.1101/2020.04.01.020966

Simplifying Glycan Profiling through a High-Throughput Micropermethylation Strategy(2020)
Shajahan A, Supekar NT, Chapla D, Heiss C, Moremen KW, Azadi P
Read Full Article: http://doi.org/10.1177/2472630320912929

New strategies for profiling and characterization of human milk oligosaccharides(2020)
Porfirio S, Archer-Hartmann SA, Moreau GB, Ramakrishnan G, Haque R, Kirkpatrick BD, Petri WA, Azadi P
Read Full Article: http://doi.org/10.1093/glycob/cwaa028

Binding of phage-encoded FlaGrab to motile Campylobacter jejuni flagella inhibits growth, downregulates energy metabolism, and requires specific flagellar glycans(2020)
Sacher JC, Shajahan A, Butcher J, Patry RT, Flint A, Hendrixson DR, Stintzi A, Azadi P, Szymanski CM
Read Full Article: http://doi.org/10.3389/fmicb.2020.00397

Exploring the scope of high throughput micro‐permethylation based glycomics(2020)
Shajahan A, Supekar NT, Heiss C, Azadi P
Read Full Article: http://doi.org/10.1096/fasebj.2020.34.s1.06510

Binding of phage-encoded FlaGrab to motile Campylobacter jejuni flagella inhibits growth, downregulates energy metabolism, and requires specific flagellar glycans(2020)
Sacher JC, Shajahan A, Butcher J, Patry RT, Flint A, Hendrixson DR, Stintzi A, Azadi P, Szymanski CM
Read Full Article: http://doi.org/10.3389/fmicb.2020.00397

Mass spectrometric method for the unambiguous profiling of cellular dynamic glycosylation(2020)
Shajahan A, Supekar NT, Wu H, Wands AM, Bhat G, Kalimurthy A, Matsubara M, Ranzinger R, Kohler JJ, Azadi P
Read Full Article:http://doi.org/10.1101/2020.05.04.075655

Species-specific recognition of Sulfolobales mediated by UV-inducible pili and S-layer glycosylation patterns(2020)
Wolferen M van, Shajahan A, Heinrich K, Brenzinger S, Black IM, Wagner A, Briegel A, Azadi P, Albers SV
Read Full Article: http://doi.org/10.1128/mBio.03014-19

Twitter Feed @CCRCUGA

Sialic acids are the queen of Glycobiology. Our new publication: Glycan Linkages Using MSn and Machine Learning─Proof of Concept Using Sialic Acid Linkages #glycotime, #glycobiology #research | Journal of the American Society for Mass Spectrometry

Finally we got this. It took years, but we have drastically improved sensitivity for composition and linkage analysis of acidic and insoluble polysaccharides. Thanks to to my talented postdoc Ian Black. #glycotime, #UGAResearch, #Glycobiology

https://pubs.acs.org/doi/10.1021/acs.analchem.3c02056

Glycobiology in Hawaii. What could be better?
Time to Register for "Glyco in Biotechnology" satellite meeting at the Society for Glycobiology.

https://lnkd.in/gBaZ7UiK

#glycotime @SFGlycobiology

Exciting new publication with our long time collaborator Adam Braunschweig from University of New York on mucomics analysis of snail and its potential use in material science. #glycotime, #glycobiology #UGAResearch

A truly kind mentor and a visionary leader in the glycoscience field. We are fortunate to have his continued friendship at the CCRC. #glycotime #UGAResearch #glycobiology #Research

I am pleased to announce a wonderful line up of speakers for the " Glyco in Biotechnology" satellite meeting at the annual Society for Glycobiology in Hawaii. Register at the SfG website #glycotime @SFGlycobiology
https://www.glycobiology.org/2023-annual-meeting

Our recent publication with a long term collaborator Stephen Free from University of Buffalo on characterization of the need for galactofuranose in fungal cell wall life cycle

#glycotime, #glycoscience , #research

All ready and excited to welcome our course participants for the 1st day of our hands on- training courses in Glycoscience at the Complex Carbohydrate Research Center #glycotime, #glycoscience #training

I am organizing the satellite meeting "Glyco in Biotechnology" at the annual Society for Glycobiology (SfG) meeting in Hawaii. If you are a company working in the Glycobiology space, contact me at azadi@uga.edu, we like to hear about your research #glycotime #Biotechnology

There is 3 weeks left to the CCRC's hands-on training courses in glycoscience. We only have a couple of spaces in each course. Register if you want to learn about in depth structural analysis of glycoconjugates #glycotime, #training. #research, #glycobiology

Load More