Iron Carbohydrate Complex

We perform dialysis and elemental analysis of iron carbohydrate complexes.

We also evaluate active ingredient sameness of the generic and innovator products and for characterization of carbohydrate starting material and iron complexes:

Glycosyl Composition Analysis

Monosaccharide composition analysis (sugar residue analysis) quantifies the residues of polysaccharides, oligosaccharides or glycoproteins by GC-MS.

Glycosyl Linkage Analysis

Linkage analysis of polysaccharides and oligosaccharides is performed by partially methylated alditol acetate (PMAA) method to determine the linkage of monosaccharides and branching points.

Molecular Weight

The approximate molecular weights of polysaccharides are measured using size exclusion chromatography (SEC). The molecular weights of oligosaccharides are measured by MALDI-MS, either non-derivatized or after derivatization.

Mass Spectrometry

We provide high resolution high sensitivity mass spectrometry analysis using electrospray and nanospray ionization, Matrix Assisted Laser Desorption Ionization (MALDI) with time of flight (TOF) as well as iontrap and orbitrap mass analyzers.

NMR Characterization (proton, carbon, COSY, TOCSY, NOESY, HSQC, HMBC)

We use both one dimensional and two dimensional nuclear magnetic resonance to determine the monosaccharide residue sequence of polysaccharides repeating units and oligosaccharides.

Impurity Profile by HPLC

High Performance Liquid Chromatography (HPLC) is a fast, robust analytical technique with a wide array of application in the laboratory.