News and Events

Primary Publications

Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern.
Shajahan A, Pepi LE, Kumar B, Murray NB, Azadi P
Sci. Rep. 2023 13(1):10053. [https://doi.org/10.1038/s41598-023-33088-0]

Pregnancy enables antibody protection against intracellular infection.
Erickson JJ, Archer-Hartmann S, Yarawky AE, Miller JLC, Seveau S, Shao Ty, Severance AL, Miller-Handley H, Wu Y, Pham G, Wasik BR, Parrish CR, Hu YC, Lau JTY, Azadi P, Herr AB, Way SS.
Nature 2022, 606(7915) 769-775. [DOI: 10.1038/s41586-022-04816-9]

A phage tail–like bacteriocin suppresses competitors in metapopulations of pathogenic bacteria. Backman T, Latorre SM, Symeonidi E, Muszyński A, Bleak E, Eads L, Martinez-Koury PI, Som S, Hawks A, Gloss AD, Belnap DM, Manuel AM, Deutschbauer AM, Bergelson J, Azadi P, Burbano HA, Karasov TL. Science 2024, 384, 1190. [DOI:10.1126/science.ado 0713].

Surface Anchoring of the Kingella kingae Galactan Is Dependent on the Lipopolysaccharide O-Antigen.
Montoya NR, Porsch EA, Muñoz VL, Muszyński A, Vlach J, Hahn DK, Azadi P, Sherman M, Yang H, Chandler CE, Ernst RK, St Geme JW 3rd. Surface Anchoring of the Kingella kingae Galactan
Read Full Article: doi: 10.1128/mbio.02295-22.

Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter.
Spellmon N, Muszyński A, Górniak I, Vlach J, Hahn D, Azadi P, Zimmer J.
Read Article: doi: 10.1038/s41467-022-32597-2.
Young ID, Nepogodiev SA, Black IM, Le Gall G, Wittmann A, Latousakis D, Visnapuu T, Azadi P, Field RA, Juge N, Kawasaki N.
Read Full Article:doi: 10.1016/j.carbpol.2021.118606.

Lipopolysaccharide associated with β-2,6 fructan mediates TLR4-dependent immunomodulatory activity in vitro. Carbohydr Polym.
Young ID, Nepogodiev SA, Black IM, Le Gall G, Wittmann A, Latousakis D, Visnapuu T, Azadi P, Field RA, Juge N, Kawasaki N.  doi: 10.1016/j.carbpol.

A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface.
Wu H, Shajahan A, Yang JY, Capota E, Wands AM, Arthur CM, Stowell SR, Moremen KW, Azadi P, Kohler JJ. A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface.
Read Full Article: doi: 10.1016/j.chembiol.2021.07.00.7

Desialylation of O-glycans activates von Willebrand factor by destabilizing its autoinhibitory module.
Voos KM, Cao W, Arce NA, Legan ER, Wang Y, Shajahan A, Azadi P, Lollar P, Zhang XF, Li R.
Read Full Article: doi: 10.1111/jth.15528.

Comprehensive characterization of N-and O-glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2(2020)
Shajahan A, Archer-Hartmann SA, Supekar NT, Gleinich AS, Heiss C, Azadi P
Read Full Article: http://doi.org/10.1101/2020.05.01.071688

Deducing the N-and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2(2020)
Shajahan A, Supekar NT, Gleinich AS, Azadi P
Read Full Article:http://doi.org/10.1101/2020.04.01.020966

Simplifying Glycan Profiling through a High-Throughput Micropermethylation Strategy(2020)
Shajahan A, Supekar NT, Chapla D, Heiss C, Moremen KW, Azadi P
Read Full Article: http://doi.org/10.1177/2472630320912929

New strategies for profiling and characterization of human milk oligosaccharides(2020)
Porfirio S, Archer-Hartmann SA, Moreau GB, Ramakrishnan G, Haque R, Kirkpatrick BD, Petri WA, Azadi P
Read Full Article: http://doi.org/10.1093/glycob/cwaa028

Binding of phage-encoded FlaGrab to motile Campylobacter jejuni flagella inhibits growth, downregulates energy metabolism, and requires specific flagellar glycans(2020)
Sacher JC, Shajahan A, Butcher J, Patry RT, Flint A, Hendrixson DR, Stintzi A, Azadi P, Szymanski CM
Read Full Article: http://doi.org/10.3389/fmicb.2020.00397

Exploring the scope of high throughput micro‐permethylation based glycomics(2020)
Shajahan A, Supekar NT, Heiss C, Azadi P
Read Full Article: http://doi.org/10.1096/fasebj.2020.34.s1.06510

Binding of phage-encoded FlaGrab to motile Campylobacter jejuni flagella inhibits growth, downregulates energy metabolism, and requires specific flagellar glycans(2020)
Sacher JC, Shajahan A, Butcher J, Patry RT, Flint A, Hendrixson DR, Stintzi A, Azadi P, Szymanski CM
Read Full Article: http://doi.org/10.3389/fmicb.2020.00397

Mass spectrometric method for the unambiguous profiling of cellular dynamic glycosylation(2020)
Shajahan A, Supekar NT, Wu H, Wands AM, Bhat G, Kalimurthy A, Matsubara M, Ranzinger R, Kohler JJ, Azadi P
Read Full Article:http://doi.org/10.1101/2020.05.04.075655

Species-specific recognition of Sulfolobales mediated by UV-inducible pili and S-layer glycosylation patterns(2020)
Wolferen M van, Shajahan A, Heinrich K, Brenzinger S, Black IM, Wagner A, Briegel A, Azadi P, Albers SV
Read Full Article: http://doi.org/10.1128/mBio.03014-19

Twitter Feed @CCRCUGA